Hull City v Newcastle (Kick-off 1:45pm)
Hull City should welcome back strikers Nikica Jelavic and Abel Hernandez for the visit of Newcastle to the KC Stadium whilst John Carver hopes to have Papiss Cisse available after the striker returned home from the African Cup of Nations following Senegal’s elimination.
Manchester United v Leicester
Michael Carrick misses the visit of Leicester after being ruled out for four weeks, but Louis van Gaal has been dealt some positive news as Ashley Young closes in on a return following a hamstring injury. Matt Upson could make his first appearance in the Leicester squad after being side-lined since July with a foot injury.
Liverpool v West Ham
Striker Daniel Sturridge is likely to make his first appearance in five months whilst Mamadou Sakho will face a late fitness test. West Ham boss Sam Allardyce is expected to be without key trio James Tomkins, Carl Jenkinson and Alex Song.
Crystal Palace v Everton
Crystal Palace midfielder Jordon Mutch is set to make his debut after joining the Eagles from QPR, but Shola Ameobi is deemed not fit enough to feature. Everton are hoping to have midfielders James McCarthy and Darron Gibson and defender Sylvain Distin back in contention.
Stoke v QPR
Stoke will be without Bojan Krkic but look set to have fellow forward Mame Biram Diouf back in their matchday squad. QPR manager Harry Redknapp is expected to have both Yun Suk-Young and Richard Dunne available again for his side’s visit to the Britannia Stadium.
Sunderland v Burnley
Lee Cattermole will be missing once again for Sunderland. Burnley have no new injury worries. Matt Taylor was unable to take part in a development game this week as he continues his recovery from Achilles surgery.
West Brom v Tottenham
New signing Callum McManaman goes straight into the squad for West Brom’s clash with Spurs, whilst Tottenham boss Mauricio Pochettino has a full squad to choose from.
Chelsea v Man City (kick-off 6:30pm)
Chelsea striker Diego Costa will miss the Premier League leaders’ showdown with Manchester City on Saturday as he starts his three-match suspension for violent conduct. Manchester City playmaker Samir Nasri could have a chance of featuring, and Frank Lampard is expected to feature in what will be his first return to Stamford Bridge as a Man City player.