Liverpool ended Arsenal’s 10-game unbeaten run in all competitions with a devastatingly routine victory at Anfield.
Sadio Mane grabbed the opener when he headed in Trent Alexander-Arnold’s free-kick in the first half.
Diogo Jota took advantage of a Nuno Tavares mistake to roll into an empty net before Mohamed Salah slotted home a Mane cross for the third.
Right-back Alexander-Arnold was the provider again when he teed up Japanese substitute Takumi Minamino to make it 4-0 with his first touch, just 48 seconds after coming on.
Victory for Liverpool sees them jump up to second in the Premier League, while Arsenal remain in fifth.
It was a tame affair between the two long-standing rivals for most of the game but Liverpool showed their quality with a ruthless second-half display.
In other matches played yesterday, Wolverhampton Wanderers striker Raul Jimenez netted a fine second-half goal to secure a 1-0 home win over high-flying West Ham United after both sides missed chances while a stunning strike by Ollie Watkins and a late goal by Tyrone Mings gave Aston Villa a 2-0 win over Brighton & Hove Albion at Villa Park in the Premier League in Steven Gerrard’s first match as their new manager.
Meanwhile, Manchester United slumped to another damaging defeat for manager Ole Gunnar Solskjaer in losing 4-1 at Watford just as Chelsea thrashed Leicester to extend their Premier League lead to six points.
Crystal Palace extended their unbeaten run in the Premier League to seven games after an entertaining 3-3 draw at Burnley while a glancing Grant Hanley header got the reign of new Norwich boss Dean Smith off to a perfect start as his side beat Southampton 2-1 in their Premier League clash on Saturday to climb off the bottom of the table.