Chelsea slumped to a first defeat to Brentford since 1939 as Christian Eriksen inspired the Bees to a 4-1 win that should seal their Premier League survival.
The European champions had gone in front early in the second half at Stamford Bridge through Antonio Rudiger’s sensational long-range strike.
Vitaly Janelt levelled just a minute later to spark a three-goal spree in 10 minutes for the visitors.
Eriksen has been in fine form since making his return to competitive football after suffering a cardiac arrest on the field during Euro 2020 made it 2-1. Janelt then made it 3-1 with a deft dink over Mendy on the hour mark.
Yoane Wissa rounded off a memorable afternoon for Thomas Frank’s men when he took advantage of more comical Chelsea defending to drill home a fourth.
A third win in four games takes Brentford up to 14th and 11 points clear of the relegation zone.
Brighton & Hove Albion and Norwich City played out a 0-0 draw at the AMEX Stadium on Saturday to end six-match losing streaks in the Premier League for both teams.
They remained rooted to the bottom of the table and seven points adrift of safety. Brighton sit comfortably mid-table in 13th place.
Wolverhampton Wanderers maintained their hopes of snatching a European spot for next season after an excellent volley from Jonny and an Ashley Young own goal helped them to a 2-1 win over Aston Villa. Villa, now winless in their last three league games, remained in ninth place on 36 points.
Manchester City moved a point clear of title rivals, Liverpool at the top of the Premier League standings with a convincing 2-0 win at relegation-threatened Burnley on Saturday.
Needing a win to reclaim the top spot after Liverpool beat Watford earlier in the day, first-half goals from Kevin de Bruyne and Ilkay Gundogan with two assists from Raheem Sterling sealed all three points for Pep Guardiola’s side.
Manchester United lost more ground in the battle for a Champions League spot as they were held by Leicester at Old Trafford.